Current listing in PubMed


Schmitter S, Fieseler L, Klumpp J, Bertram R, Loessner MJ. (2017) TetR-dependent gene regulation in intracellular Listeria monocytogenes demonstrates the spatiotemporal surface distribution of ActA. Mol Microbiol. 2017 May 15. doi: 10.1111/mmi.13706. [Epub ahead of print][PubMed]


Xu T, Wu Y, Lin Z, Bertram R, Götz F, Zhang Y, Qu D. (2017) Identification of Genes Controlled by the Essential YycFG Two-Component System Reveals a Role for Biofilm Modulation in Staphylococcus epidermidis. Front Microbiol. 2017 Apr 26;8:724. doi: 10.3389/fmicb.2017.00724. eCollection 2017. [PubMed]


Meiers M, Laux A, Eichinger D, Sexauer A, Marx P, Bertram R, Brückner R. (2017) A tetracycline-inducible integrative expression system for Streptococcus pneumoniae. FEMS Microbiol Lett. 2017 Mar 1;364(5). doi: 10.1093/femsle/fnx044. [PubMed]


Schuster, C. F. and Bertram, R. (2016) Toxin-Antitoxin Systems of Staphylococcus aureus. Toxins 2016, 8, 140; doi:10.3390/toxins8050140 [Fulltext]


Bertram, R. (2016) Persisters run out of fuel. Nature Microbiol. 1 (2016). [ReadCube]


Prax, M., Mechler, L., Weidenmaier, C. and Bertram, R. (2016) Glucose Augments Killing Efficiency of Daptomycin Challenged Staphylococcus aureus Persisters. PLoS One. 2016 Mar 9;11(3):e0150907. doi: 10.1371/journal.pone.0150907. eCollection 2016. [PubMed]


Mechler, L., Bonetti, E. J., Reichert, S., Flötenmeyer, M., Schrenzel, J., Bertram, R., François, P. and Götz F. (2016) Daptomycin tolerance in the Staphylococcus aureus pitA6 mutant is due to upregulation of the dlt-operon. Antimicrob Agents Chemother. 2016 Apr 22;60(5):2684-91. doi: 10.1128/AAC.03022-15. Print 2016 May. [PubMed]


Bertram, R. (2016) Complementation Plasmids, Inducible Gene-Expression Systems, and Reporters for Staphylococci. Methods Mol Biol.2016;1373:25-32. doi: 10.1007/7651_2014_181 [PubMed]


Mechler, L., Herbig, A., Paprotka, K., Fraunholz, M., Nieselt, K. and Bertram, R. (2015). A Novel Point Mutation Promotes Growth Phase-Dependent Daptomycin Tolerance in Staphylococcus aureus. Antimicrob Agents Chemother. 2015 Sep;59(9):5366-76. doi: 10.1128/AAC.00643-15. Epub 2015 Jun 22.
[PubMed]


Schuster, C. F., Mechler, L., Nolle, N., Krismer, B., Zelder, M. E., Götz, F. and Bertram, R. (2015). The MazEF Toxin-Antitoxin System Alters the β-Lactam Susceptibility of Staphylococcus aureus. PLoS One. 2015 May 12;10(5):e0126118. doi: 10.1371/journal.pone.0126118. eCollection 2015 [PubMed]


Schuster, C. F. and Bertram R. (2014). Fluorescence Based Primer Extension Technique to Determine Transcriptional Starting Points and Cleavage Sites of RNases In Vivo.
J Vis Exp. 2014 Oct 31;(92). doi: 10.3791/52134. [PubMed]


Prax, M. and Bertram R. (2014). Metabolic aspects of bacterial persisters. Front Cell Infect Microbiol. 2014 Oct 22;4:148. eCollection 2014. Review. [PubMed]


Koczula, A., Willenborg, J., Bertram, R., Takamatsu, D., Valentin-Weigand, P. and Goethe, R. (2014).
Establishment of a Cre recombinase based mutagenesis protocol for markerless gene deletion in Streptococcus suis. J Microbiol Methods. 2014 Dec;107:80-3. doi: 10.1016/j.mimet.2014.09.007. Epub 2014 Oct 1 [PubMed]


Lechner, S.*, Prax, M.*, Lange, B., Huber, C., Eisenreich, W., Herbig, A., Nieselt, K. and Bertram R. (2014). Metabolic and transcriptional activities of Staphylococcus aureus challenged with high-doses of daptomycin. Int J Med Microbiol. 2014 May 28. pii: S1438-4221(14)00059-9. doi: 10.1016/j.ijmm.2014.05.008. [Epub ahead of print] (* equally contributing authors) [PubMed]


Willenborg, J., Willms, D., Bertram, R., Goethe, R. and Valentin-Weigand, P. (2014). Characterization of multidrug tolerant persister cells in Streptococcus suis. BMC Microbiol. 2014 May 12;14(1):120. doi: 10.1186/1471-2180-14-120. [PubMed]


Bertram, R. and Schuster C. F. (2014). Post-transcriptional regulation of gene expression in bacterial pathogens by toxin-antitoxin systems. Front Cell Infect Microbiol. 2014 Jan 29;4:6. doi: 10.3389/fcimb.2014.00006. eCollection 2014. Review. [PubMed]


Hartmann, T., Zhang, B., Baronian, G., Schulthess, B., Homerova, D., Grubmüller, S., Kutzner, E., Gaupp, R.,
Bertram, R., Powers, R., Eisenreich, W., Kormanec, J., Herrmann, M., Molle, V., Somerville, G. A. and Bischoff, M. (2013). Catabolite control protein E (CcpE) is a LysR-type transcriptional regulator of TCA cycle activity in Staphylococcus aureus. J Biol Chem. 2013 Dec 13;288(50):36116-36128 [PubMed]


Yu, W.*, Leibig, M.*, Schäfer, T., Bertram, R., Ohlsen, K. and Götz, F. (2013). Mevalonate auxotrophic mutant of Staphylococcus aureus can adapt to mevalonate depletion. Antimicrob Agents Chemother. 2013 Nov;57(11):5710-5713 (* equally contributing authors) [PubMed]


Nolle, N.*, Schuster, C. F.* and Bertram, R. (2013). Two paralogous yefM-yoeB loci from Staphylococcus
equorum
encode functional toxin-antitoxin systems. Microbiology 2013 Aug;159(Pt 8): 1575-1585 (* equally
contributing authors) [PubMed]


Prax, M., Lee, C. Y. and Bertram, R. (2013). An update on the molecular genetics toolbox for staphylococci.
Microbiology 2013 Mar;159(Pt 3):421-434 [PubMed]


Schuster, C. F. and Bertram, R. (2013). Toxin-antitoxin systems are ubiquitous and versatile modulators of
prokaryotic cell fate. FEMS Microbiol Lett. 2013 Mar;340(2):73-85 [PubMed]


Lechner, S., Patra, P., Klumpp, S. and Bertram, R. (2013). Interplay between population dynamics and and drug tolerance of Staphylococcus aureus persister cells. J Mol Microbiol and Biotechnol. 2013 Jan 25;22(6):381-391 [PubMed]


Schuster, C. F., Park J. H., Prax M., Herbig A., Nieselt K., Rosenstein R., Inouye, M. and Bertram, R. (2013). Characterization of a mazEF toxin-antitoxin homologue from Staphylococcus equorum. J Bacteriol. 2013 Jan;195(1):115-25 [PubMed]


Lechner, S., Lewis, K. and Bertram, R. (2012). Staphylococcus aureus persisters tolerant to bactericidal
antibiotics. J Mol Microbiol and Biotechnol. 2012;22(4):235-244 [PubMed]


Gauger, T., Weihs, F., Mayer, S., Krismer, B., Liese, J., Kull, M. and Bertram, R. (2012). Intracellular monitoring oftarget protein production in Staphylococcus aureus by peptide tag-induced reporter fluorescence. Microb Biotechnol 2012 Jan;5(1):129-134 [PubMed]


Helle, L.*, Kull, M.*, Mayer, S., Marincola, G., Zelder, M.-E., Goerke, C., Wolz, C. and Bertram, R. (2011). Vectors for improved Tet repressor -dependent gradual gene induction or silencing in Staphylococcus aureus. Microbiology 2011 Dec;157(Pt 12):3314-3323 (* equally contributing authors) [PubMed]


Bertram, R.*, Rigali, S.*, Wood, N., Lulko, A. T., Kuipers O. P. and Titgemeyer, F. (2011). Regulon of the N-Acetylglucosamine Utilization Regulator (NagR) in Bacillus subtilis. J Bacteriol 2011 Jul;193(14):3525-3536 (* equally contributing authors) [PubMed]


Stary, E.*, Gaupp, R.*, Lechner, S., Leibig, M., Tichy, E., Kolb, M. and Bertram, R. (2010). New architectures for Tet-ON and Tet-OFF regulation in Staphylococcus aureus. Appl Environ Microbiol. 2010 Feb;76(3):680-687 (* equally contributing authors) [PubMed]


Biswas, L., Biswas, R., Schlag, M., Bertram, R. and Götz, F. (2009). Small-colony variant selection as a survival strategy for Staphylococcus aureus in the presence of Pseudomonas aeruginosa. Appl Environ Microbiol. 2009 Nov;75(21):6910-6912 [PubMed]


Bertram, R., Kolb, M. and Hillen, W. (2009). In vivo activation of Tetracycline repressor by Cre/lox mediated gene assembly. J Mol Microbiol and Biotechnol 17(3):136-145 [PubMed]


Resch, M., Roth H. M., Kottmair, M., Sevvana, M., Bertram, R., Titgemeyer, F. and Muller, Y. A. (2009). Cloning, expression, purification, crystallization and preliminary X-ray diffraction analysis of YvoA from Bacillus subtilis. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2009 Apr;65(4): 410-414 [PubMed]


Leibig, M.*, Krismer, B.*, Kolb, M., Friede, A., Götz, F., and Bertram, R.(2008). Marker removal in staphylococci via Cre recombinase and different lox sites. Appl Env Microbiol 2008 Mar;74(5):1316-1323 (* equally contributing authors) [PubMed]


Bertram, R. and Hillen, W. (2008). The application of Tet repressor in prokaryotic gene
regulation and expression. Microb Biotechnol 2008 Jan;1(1):2-16 [PubMed]


Kamionka, A., Majewski, M., Roth, K., Bertram, R., Kraft, C. and Hillen, W. (2006). Induction of tetracycline repressor requires the binding of two inducers. Nucleic Acids Res 2006;34(14):3834-3841 [PubMed]


Köstner, M., Schmidt, B., Bertram, R. and Hillen, W. (2006). Generating tetracycline inducible auxotrophy in
Escherichia coli and Salmonella enterica serovar Typhimurium by using an insertion element and a hyperactive transposase. Appl Env Microbiol 2006 Jul;72(7):4717-4725 [PubMed]


Bertram, R., Wünsche, A., Sprehe, M. and Hillen, W. (2006) Regulated Expression of HPrK/P does not affect Carbon Catabolite Repression of the xyn Operon and of rocG in Bacillus subtilis. FEMS Microbiol Lett. 2006 Jun;259(1):147-152 [PubMed]


Bertram, R., Köstner, M. Müller, J., Vazquez Ramos, J. and Hillen, W. (2005). Integrative elements for Bacillus subtilis yielding tetracycline-dependent growth phenotypes. Nucleic Acids Res 2005 Oct;33(18):e153 [PubMed]


Henßler, E. M., Bertram, R., Wisshak, S. and Hillen, W. (2005). Tet repressor mutants with altered effector binding and allostery. FEBS Journal 2005 Sep;272(17):4487-4496 [PubMed]


Bertram, R., Kraft, C., Wisshak, S., Müller, J., Scholz, O. and Hillen, W. (2004). Phenotypes of combined Tet repressor mutants for effector and operator recognition and allostery. J Mol Microbiol and Biotechnol
2004;8(2):104-110 [PubMed]


Kamionka, A., Bertram, R. and Hillen, W. (2005). Tetracycline dependent conditional gene knockout in Bacillus subtilis. Appl Env Microbiol 2005 Feb;71(2):728-733 [PubMed]


Scholz, O., Henßler, E. M., Bail, J., Schubert, P., Bogdanska-Urbaniak, J., Sopp, S., Reich, M., Wisshak, S.,
Köstner, M., Bertram, R. and Hillen, W. (2004). Activity reversal of Tet repressor by single amino acid exchanges. Mol Microbiol 2004 Aug;53(3):777-789 [PubMed]


Bertram, R., Schlicht, M., Mahr, K., Nothaft, H., Saier, M. H. jr. and Titgemeyer F. (2004). In silico and
transcriptional analysis of carbohydrate uptake systems of Streptomyces coelicolor A3(2). J Bacteriol 2004
Mar;186(5):1362-1373. [PubMed]


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